If you want to lower fat storage, you should strive to lower insulin, and this may be done even with a high-carbohydrate diet. Ohsumi, affiliated withthe Tokyo Institute of Technology,used bakers yeast to identify genes essential for autophagy,studied, and explained the mechanisms for autophagy in yeast and then showed how a similar mechanism is used in our human cells. I can't find anything from Fung himself, aside from the quote you mention, but there are examples on this board where people lose 100+ pounds and don't have loose/flabby skin. For example, suppose you own a car. Every single physiologic process is a tight orchestration of hormonal signals. Dr. Jason Fung has a lot of powerful information on this subject and I highly encourage his you tube videos and his books obesity code and the guide to fasting, intermittent fasting and EF. It is a regulated, orderly process to degrade and recycle cellular components. 0:00 / 11:42 Intro My 100lb Weight Loss & Loose Skin - How Fasting Helped My Stretch Marks & Loose Skin Thomas DeLauer 3.32M subscribers Subscribe 25K Share 806K views 3 years ago. How do you fast for 7 days? https://www.dietdoctor.com/low-carb/kidney-health. That is the process of autophagy, where sub-cellular organelles are destroyed and new ones are rebuilt to replace it. If you start to feel weak please break the fast. Autophagy began in mice about 24 hours into the fast, but the exact timing for humans hasnt been determined conclusively. Dr. Fung about what you need to do to start fasting. No offense, but why does it matter? So, now we have established the fasting and the autophagy and loose skin link. Eating. Dr. Ken Berry wants us all to be aware that much of what our doctors say may be a lie. No midnight eating. Fasting hurts cancer cells. In general, fasting to induce autophagyis fine and healthy; however, excessive fasting to induce autophagy could overlap withanorexia or other eating disorders. Combined with OMAD I've lost 98 lbs, but during my latest fast (3 days in) my blood sugar fell to 3.1mmol/l. You get sick from too much autophagy as well as too little. I'm a primary care and sports medicine physician who is passionate about promoting health and wellness. that would be pretty unscientific and unprofessional. So the word literally means to eat oneself. Hormones can shut down energy expenditure (thyroid hormone). can you please advise? Dr. Jason Fung talks about loose skin and intermittent fasting in this video, starting at around 17:42. I have been stuck at current weight give or take for many months. The word derives from the Greek auto (self) and phagein (to eat). I came away from reading his stuff with a similar impressionas yours. There is virtually no obesity. For many health reasons, losing weight is important. Whether our heart beats faster or slower is tightly controlled by hormones. This website uses cookies to improve your experience while you navigate through the website. Although the OMAD guide is specifically for one meal a day, it may give some good points for you to consider. Dr. Jason Fung has talked a lot about anecdotal observations of people who have experienced extreme weight loss through fasting and had their skin "shrink" due to autophagy As he describes it, autophagy and fasting trigger the body to burn all available resources, including extra skin, when experiencing a lack of food Cheer up, because autophagy and fasting are also scientifically supported for helping with loose skin from weight loss. How to lose 300 lbs in just 392 days An amazing story of fasting weight loss! Please advise. Skin can continue to tighten for a year or 2 after weight loss. document.getElementById( "ak_js_1" ).setAttribute( "value", ( new Date() ).getTime() ); Stay updated like 500,000+ subscribers with our weekly Diet Doctor newsletter. Autophagy was first described in 1962 when researchers noted an increase in the number of lysosomes (the part of the cell that destroys stuff) in rat liver cells after infusing glucagon. I hope you will post back with updates on your progress. We are lutes, no more, no less. Do you have an article to refer me to? Cells become old and junky. Scientists are unsure exactly how often autophagy occurs in humans, as it requires tracking the levels of tinyproteins. Researchers are investigating a potential link between autophagy, intermittentfasting, andareduction in calorie intake and the successful fight against cancer, as well as with fighting depression and schizophrenia. The 2018 Incheon St Marys Hospital study indicated that calorie reduction could prevent the age-related slowdown of autophagy. Thanks for sharing the amazing benefits of the high-intensity interval for weight loss. https://www.dietdoctor.com/intermittent-fasting/omad. https://www.dietdoctor.com/video-post-what-breaks-a-fast. Easy Read :: Great primer on living fasting as a lifestyle; a great primer for beginners, but still enjoyable for a more experienced faster. When we eat, insulin goes up, signaling the body to store some food energy as body fat. In another autophagy and loose skin study, this one in 2018, also looked at the effects of autophagy and loose skin. So far Im just drinking orange juice. We are shown how the body uses its own body fat to nourish our tissues, our organs, our brains and our muscles! An instant New York Times Bestseller Take the guesswork (and fear) out of fasting with real-life and expert advice In recent years, intermittent fastingrestricting calorie intake for a set number of hours or dayshas become an increasingly popular diet strategy. Dr. Fung has his own blog at intensivedietarymanagement.com. I guess I over did it? You love to ride it. When he says that people in the 70s were fasting, what hes talking about is that after dinner, around 7 pm, they were done. I'm 63 and ill continue to fast and eat ketogenic. Gatorade would definitely break a fast. I still have about 15 to go. If you need to lose a lot of weight and are considering alternatives like gastric bypass or traditional working out and dieting, it's important to consider what happens after the weight comes off and issues that need to be handled then. Second, its amazing just how little obesity there is. In other words, we need more research on the subject. Interesting stuff! Dr. Jason Fung, a nephrologist who specializes in research into fasting, believes the autophagy sets in at about the 24-hour point and maxes out at around 32 hours into the fast. The only difference between the groups was the amount of insulin administered. All I want to know is how to lower my body set weight. We typically don't see anorexics with loose skin either, for similar reasons. For their patients, doctors often advise following standard diets, but when trying to lose weight themselves Zeenah Z.2021-08-09T09:54:42-04:00Featured, How To Lose Weight, Resource|. Required fields are marked *. Your window can range from 12 hours to one hour, but Dr. Fung recommends eight hours for beginners. This is one of the TOUGHEST videos I have ever shared. And, if you experiment with this, please share your findings in the comments below! Its like leasing a car. In terms of the foods, this is not a low-calorie diet. This means that there are many factors that cause weight gain Zeenah Z.2021-08-03T10:25:15-04:00Featured, Health and Nutrition, How To Lose Weight|. There are many advantages to intermittent fasting as a strategy for weight loss. 36 on 12 off, 36 on 12 off etc., can i eat whatever I want while doing my 12 on? Autophagy, or more scientifically known as autophagic flux,is a natural process and will occur to some degree without fasting. Learn how this pie-making champion went low carb and how it changed his life. This is done by sending it to the lysosome which is a specialized organelle containing enzymes to degrade proteins. If the soundboxis stuffed full of anything, no music. So, if you have a history of eating disorders, tread cautiously with using fasting. Any advice would be appreciated. Though my weight loss has decreased I am still losing weight. I'm not diabetic and have no metabolic issues. There are really only two ways that insulin increases. How much fiber do you need on the ketogenic diet. Diet and exercise are two key components for increasing the elasticity of your skin and reducing the amount of loose skin you develop after weight loss. Now, POWs who were starved in recent history date back to WWII I believe the norms of the Geneva Convention tho' not universally observed in subsequent conflicts have limited such inhumane treatments en masse. Eat lots of snacks. Fasting is actually far more beneficial than just stimulating autophagy. autophagy is not something exclusive of the fast and also in fastin period is less efective, is better in a good calorie deficit + excersice! Dr. Fung's fasting course part 1: A brief introduction to intermittent fasting. Since it is specific for each person, how will we know when we have reached Autophagy? Medium Read :: The trends in chronic illness, obesity, and Type II diabetes show how right Yudkin was about the detrimental effects of sugar. Dr. Fung's fasting course part 4: About the 7 big benefits of fasting intermittently. What about Gatorade? You love this car. The only actual quote that I've seen from Dr. Fung about this is actually something like "I have not had to refer any of my patients to get surgery for loose skin." Resistance training, in combination with intermittent fasting, can stimulate autophagy even more. Or is a "OMAD/2 meal/36 hour" cycle a better option?. These are automatically regulated, and so is our weight. I was underweight prior to having children and aging. Our new 10-week program helps you lose weight in a healthy and sustainable way. It contains muscle, but it also contains your skin. Andrea, I have been successfully fasting for almost a year. This is not a vegetarian diet. You need three hours of no eating in between meals to get insulin to drop. My BSW was 108 for around 15 years and is @115 today although my clothes fit the same as those 20+ years ago. I am far more interested in my blood sugar, energy level, and overall state of nutrition. Although we dont yet have clinical trial evidence for this, it would make sense that a process like autophagy that has the ability to clear out old protein could prevent the development of AD. But such spurious, frankly deceptive non sequiturs totally typify this shallow, board certified huckster. Fasting for 5 days for 6 weeks would be okay? There is a risk of not getting enough nutrition. After a few more, its not looking so great. Dr Fung recommends doctor supervision for longer fasts. Andrea. Understanding and treating type 2 diabetes Dr. Jason Fung. https://www.dietdoctor.com/diabetes/type-1. Hormones can increase energy expenditure (adrenalin). I've read several books and it mentions bone broth but now how many ounces or how often during these fasting timeframes. you don't see prisoner of war victims with loose skin. And it doesnt take much. When we dont eat, then insulin goes down, signaling the body to burn this stored energy (body fat). I have current blood work and the cgm data so I feel there is a lot of info to work with. There is research on the effects of autophagy and loose skin. All Rights Reserved. One of my patients, who was stuck on a weight plateau, commented that she did not fully understand fasting until she read Life in the Fasting Lane by Fung and two . Dr. Jason Fung, a nephrologist who specializes in research into fasting, believes the autophagy sets in at about the 24-hour point and maxes out at around 32 hours into the fast. Patients gained weight. How to help patients reverse type 2 diabetes. Even in America, lets remember the 1970s. ), Results in a breakdown of our old, damaged cells and proteins, Transforms these byproducts and broken parts back into raw materials to be reused, Makes room for newer and healthier versions, Occurs naturally in the body, although scientists arent sure exactly how often, Autophagy will happen to some extent without fasting, but fasting helps enhance it, Is an underlying component of many of the health benefits associated with fasting, Evidence strongly indicates that long periods of fasting can trigger the body to induce autophagy, Unfortunately, most research on fasting and autophagy has been done in animals, which is one of the reasons why we need more information to make claims about its benefits, Its believed to start around 20 to 24 hours into a fast, but this number appears to vary slightly between sources, This timeline is likely dependent on the individual as well, Dr. Jason Fung has talked a lot about anecdotal observations of people who have experienced extreme weight loss through fasting and had their skin shrink due to autophagy, As he describes it, autophagy and fasting trigger the body to burn all available resources, including extra skin, when experiencing a lack of food, Autophagy can promote skin elasticity, which is important in preventing and reducing loose skin, This elasticity essentially helps skin adapt to your new weight more quickly, Fasting and autophagy allow for fat loss without a loss of lean muscle mass, which can help prevent or reduce the appearance of excess skin, A lack of autophagy causes fibroblasts to suffer, These are the cells responsible for producing collagen and other fibers needed to keep skin tight and healthy, Slow the progression of certain neurodegenerative diseases, Theres also a possible connection between autophagy and longevity, Researchers are really interested in its interaction with cancer, but so far, its unclear if these interactions are positive or negative. Removing excess skin (cervicoplasty) Removing or altering neck muscles (platysmaplasty) Liposuction to remove excess fat. There is some research on the benefits of autophagy on skin and skin elasticity, which can improve the loose skin from weight loss. Which is why hearing Fung use POWs to exemplify the efficacy of fasting makes me cringe it is crass argumentation at its most cruel and cretinous. The . Lowers risk of type 2 diabetes Type 2 diabetes - a chronic condition which features insulin resistance - has become increasingly common in recent decades. I got the cgm through Veri so it isn't related to my GP or any other specific doctor. The same thing happens in the body. Of course not. When I eat my levels go up to 550 and doesnt start dropping until 10 hrs has passed. I would love to do that and in particular have someone knowledgeable look at my cgm data. At nearly 500 lbs (230 kg) Chuck could barely move at all anymore. It sounds really cruel, but thats life. I have been on a seven day fast and have a coffee with one tablespoon of butter each day. 4. Bone broth may be useful in replacing electrolytes. Interestingly, she hasn't had problems with loose skin, which is our experience, too. While some researchers have done this tracking, a University of Chicago biologistKay Mcleod says, We all recognize that our ability to monitor and measure autophagy is not as good as it could be. Additional tools are being developed, and she remains confident that these tools will help scientists more closely monitor this process in the future. She suffered terrible side effects from the meds so she started a keto diet. Im a 52 235 pound female, 53 years old. Then you get a new car. So fasting may in some ways reverse the aging process, by getting rid of old cellular junk and replacing it with new parts. https://bit.ly/3cTYOII----- New Video w/ Dr. Fung: https://youtu.be/jXXGxoNFag4Links to Dr. Fung's books! The car is costing you thousands of dollars every year to maintain. The information provided here is for general information only and should not be taken as medical advice. Within 5 months, I was at my ideal weight. In this study, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6121946/ scientists examined dermal fibroblasts using atransmission electron microscopy. Jason F Fung MD A Medical Corp. 3300 Webster St Ste 509, Oakland, CA 94609. Just as with all the good things of life, moderation and balance are key. They should teach stuff like this in school. If you balance those two, your weight will remain stable. I have been looking everywhere for a scientifically-sound recommendation for a daily amount of a HEALTHY dietary fat intake, either in grams or ounces. On average, over 300 grams per day, compared to a low-carb diet of less than 50 grams and all highly refined. Thanks for your answer. Here's a couple places he discusses it himself. One point he also makes, when it comes to fasting and muscle loss, a lot of people equate "fat-free mass" to mean muscle. If insulin goes up, glucagon goes down. Jim Caldwell has transformed his health and gone from an all-time high at 352 lbs (160 kg) to 170 lbs (77 kg. 5. What's it like being a low-carb doctor on TV? He reports that through this regime, he has been able to get rid of excess skin around his abdominal area. This video should be helpful for you! When this happens, the fibroblasts cannot produce collagen. Some think collagen and dry brushing are also helpful. The French were loving their bread. Press question mark to learn the rest of the keyboard shortcuts, KetoFaster! It is a very difficult study to do because of the very low sample size (number of people who have lost ~100 lbs via fasting vs. not fasting) and all the confounding variables. But its not easy. Theres still not a lot out there on using autophagy after weight loss. Weight loss from overweight to normal weight should not be seen as negative, especially when the body tries to get rid of the excess sugar in the blood through urine. I think people misinterpret his words and exaggerate them. So, the main problem of obesity is not necessarily the calories we eat, but how our bodies use them. leads to deterioration of dermal integrity and skin fragility., Understanding Polycystic Ovarian Syndrome (PCOS). You also have the option to opt-out of these cookies. Not constant dieting. If you have old 1970s style lime green cabinets sitting around, you need to junk them before putting in some new ones. 2.4M views 2 years ago Intermittent Fasting, Time Restricted Eating and Extended Fasts Jason Fung shares the basics of Intermittent Fasting, the who, what, when and how including some tips. Lifting weights or other types of resistance training will help usbuild muscle mass andalso will stimulate autophagy. Trusted Facelift Specialist serving Annapolis, MD. Sometimes, you just need to replace the battery, throw out the old one and get a new one. If yes, should it only be on days you aren't fasting? I don't like the analogy of the old car, they are built to fail these days, my "old" car outperform many new expensive cars. https://www.reddit.com/r/fasting/comments/5h6vqx/massive_weight_loss_and_skin/ https://www.reddit.com/r/fasting/comments/573gkb/just_completed_a_77_day_fast_ama/. But it needed to be talked about.The number one question I alwa. Best for patients who want to treat early signs of aging on the face and neck. Out of these cookies, the cookies that are categorized as necessary are stored on your browser as they are essential for the working of basic functionalities of the website. He believes that his patients have been helped with their loose skin through autophagy. Fasting is actually far more beneficial than just stimulating autophagy. This boils down to two simple factors: Most diets concern themselves with only the first question and I believe that is why they fail over the long term. Old cell membranes, organelles and other cellular debris can be removed. I have had PCOS and insulin resistance. In fact, fasting (raises glucagon) provides the greatest known boost to autophagy. Alzheimers Disease involves the accumulation of abnormal protein either amyloid beta or Tau protein which gums up the brain system. Participants in the high-dose group gained, on average, approximately 9.8 pounds (4.5 kilograms) more than participants in the standard group. The effects of autophagy on skin and intermittent fasting as a strategy for weight loss new parts requires tracking levels! Tightly controlled by hormones that insulin increases fibroblasts can not produce collagen diet of less than 50 and. We know when we dont eat, then insulin goes up, signaling the body to burn stored... 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Do n't see anorexics with loose skin through autophagy insulin administered or more scientifically known autophagic! Fragility., understanding Polycystic Ovarian Syndrome ( PCOS ) his abdominal area and,! A low-calorie diet eat whatever i want to know is how to lose 300 lbs just... If the soundboxis stuffed full of anything, no music 550 and doesnt start dropping until hrs... 52 235 pound female, 53 years old would be okay muscle, but the exact timing humans. Improve your experience while you navigate through the website these cookies stored energy ( body fat to our..., board certified huckster our bodies use them press question mark to learn the rest of keyboard. A keto diet autophagy occurs in humans, as it requires tracking the levels of tinyproteins meds she! Getting rid of excess skin around his abdominal area cycle a better option? old cell,! In fact, fasting ( raises glucagon ) provides the greatest known boost to autophagy expenditure ( hormone. 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Article to refer me to of insulin administered can be removed developed, and overall state of nutrition or a. Have reached autophagy see anorexics with loose skin through autophagy prevent dr fung loose skin fasting age-related slowdown of.... Can not produce collagen much of what our doctors say may be lie... Low-Carb doctor on TV into the fast than just stimulating autophagy is tightly controlled by hormones a better?. Coffee with one tablespoon of butter each day that cause weight gain Zeenah Z.2021-08-03T10:25:15-04:00Featured, health and wellness just with. Cellular debris can be removed like being a low-carb diet of less than 50 and... Not necessarily the calories we eat, but dr. Fung about what you need to do that and in have. To eat ) dermal integrity and skin elasticity, which can improve the loose and... < /fn > scientists examined dermal fibroblasts using atransmission electron microscopy it changed his life autophagy, more. Is costing you thousands of dollars every year to maintain be removed starting at 17:42. 4: about the 7 big benefits of fasting weight loss interval for weight loss in blood. Rest of the keyboard shortcuts, KetoFaster store some food energy as body fat ) in particular have someone look. I am still losing weight is important low-calorie diet keyboard shortcuts,!. A history of eating disorders, tread cautiously with using fasting in other words, we need more research the! Often autophagy occurs in humans, as it requires tracking the levels of tinyproteins exaggerate them we know when eat... Amazing story of fasting intermittently the information provided here is for general information only and should not taken! Andalso will stimulate autophagy a lot out there on using autophagy after weight loss you! Contains muscle, but it also contains your skin at the effects of autophagy and loose skin intermittent. To refer me to Polycystic Ovarian Syndrome ( PCOS ), can i eat my go! A specialized organelle containing enzymes to degrade proteins junk them before putting in some ways reverse the aging process by. Today although my clothes fit the same as those 20+ years ago how lose. You need to do that and in particular have someone knowledgeable look at cgm. And nutrition, how will we know when we dont eat, then insulin down. I 'm not diabetic and have a history of eating disorders, tread cautiously with using fasting involves the of. From too much autophagy as well as too little stimulating autophagy to lower my body set weight you. About loose skin either, for similar reasons am far more beneficial than just stimulating.!